产品
编 号：F270155
分子式：C30H39NO2
分子量：445.64
分子式：C30H39NO2
分子量：445.64
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CAS No: 2102494-14-2
产品详情
生物活性：
OP-3633 is a potent and selective steroidal glucocorticoid receptor (GR) antagonist with an IC50 of 29 nM, with inhibition of GR transcriptional activity. OP-3633 exhibits low progesterone receptor (PR) agonism and androgen receptor (AR) antagonism.
体外研究：
OP-3633 exhibits low progesterone receptor (PR) agonism with an EC50 higher than 2500 nM. OP-3633 exhibits low androgen receptor (PR) antagonism, with an IC50 of 1135 nM.
OP-3633 is a potent and selective steroidal glucocorticoid receptor (GR) antagonist with an IC50 of 29 nM, with inhibition of GR transcriptional activity. OP-3633 exhibits low progesterone receptor (PR) agonism and androgen receptor (AR) antagonism.
体外研究：
OP-3633 exhibits low progesterone receptor (PR) agonism with an EC50 higher than 2500 nM. OP-3633 exhibits low androgen receptor (PR) antagonism, with an IC50 of 1135 nM.
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