产品
编 号：F269949
分子式：C34H44N6O6
分子量：632.75
分子式：C34H44N6O6
分子量：632.75
产品类型
规格
价格
是否有货
1mg
询价
询价
5mg
询价
询价
10mg
询价
询价
25mg
询价
询价
结构图
CAS No: 2101208-44-8
产品详情
生物活性：
CM03 is a potent DNA G-quadruplexes (G4s) ligand. CM03 can stabilise G4s, downregulating more G4-containing genes as well as increasing incidence of double-strand break events (DSBs) due to torsional strain on DNA and chromatin structure. CM03 has selective potency for pancreatic cancer cells.
体外研究：
CM03 (0.4 μM; 24 or 48 h) increases the level of γ-H2AX protein when in combination with SAHA (HY-10221) in MIA PaCa-2 and PANC-1.CM03 (0-100 nM; 96 h) exhibits highly anti-proliferative activity against pancreatic cancer cell lines.
CM03 is a potent DNA G-quadruplexes (G4s) ligand. CM03 can stabilise G4s, downregulating more G4-containing genes as well as increasing incidence of double-strand break events (DSBs) due to torsional strain on DNA and chromatin structure. CM03 has selective potency for pancreatic cancer cells.
体外研究：
CM03 (0.4 μM; 24 or 48 h) increases the level of γ-H2AX protein when in combination with SAHA (HY-10221) in MIA PaCa-2 and PANC-1.CM03 (0-100 nM; 96 h) exhibits highly anti-proliferative activity against pancreatic cancer cell lines.
产品资料
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