产品
编 号：F269633
分子式：C40H40N10O8S2
分子量：852.94
分子式：C40H40N10O8S2
分子量：852.94
产品类型
规格
价格
是否有货
1mg
询价
询价
5mg
询价
询价
10mg
询价
询价
结构图
CAS No: 2098487-75-1
产品详情
生物活性：
PROTAC Sirt2 Degrader-1 is a SirReal-based PROTAC, acts as a Sirt2 degrader, composed of a highly potent and isotype-selective Sirt2 inhibitor, a linker, and a bona fide Cereblon ligand for E3 ubiquitin ligase. PROTAC Sirt2 Degrader-1 shows an IC50 of 0.25 μM for Sirt2, with no effect on Sirt1/Sirt3 (IC50s>100 μM).
体外研究：
PROTAC Sirt2 Degrader-1 (化合物 12；10 μM，1-6 小时) 在 HeLa 细胞中诱导 Sirt2 降解。
PROTAC Sirt2 Degrader-1 is a SirReal-based PROTAC, acts as a Sirt2 degrader, composed of a highly potent and isotype-selective Sirt2 inhibitor, a linker, and a bona fide Cereblon ligand for E3 ubiquitin ligase. PROTAC Sirt2 Degrader-1 shows an IC50 of 0.25 μM for Sirt2, with no effect on Sirt1/Sirt3 (IC50s>100 μM).
体外研究：
PROTAC Sirt2 Degrader-1 (化合物 12；10 μM，1-6 小时) 在 HeLa 细胞中诱导 Sirt2 降解。
产品资料
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