产品
编 号:F259493
分子式:C20H23N9O
分子量:405.46
产品类型
结构图
CAS No: 2097252-39-4
联系客服
产品详情
生物活性:
CHK1-IN-3 is a Checkpoint Kinase 1 (CHK1) inhibitor with an IC50 of 0.4 nM.
体内研究:
CHK1-IN-3 significantly suppresses the tumor growth in Z-138 cell inoculated xenograft model as a single agent with body weight unaffected.
体外研究:
CHK1-IN-3 effectively inhibites the growth of malignant hematopathy cell lines especially Z-138 (IC50: 0.013 μM) and displays low affinity for hERG (IC50 > 40 μM).