产品
编 号：F259462
分子式：C27H31FN6O
分子量：474.57
分子式：C27H31FN6O
分子量：474.57
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CAS No: 2096999-92-5
产品详情
生物活性：
JAK-IN-5 is an inhibitor of JAK extracted from patent US20170121327A1, compound example 283.
体内研究：
JAK-IN-5 (compound 1) (oral aspirate, 0.5 mg/mL, 50 μL ) inhibits STAT6 phosphorylation by 60% in IL-13-induced in lung tissue in a mouse model of pSTAT6 induction.JAK-IN-5 (compound 1) (oral aspirate, 0.1-1.0 mg/mL, 50 μL) inhibits 88% of BALF eosinophils in male C57 mice model of Alternaria alternata-induced eosinophilic inflammation of the lung.
JAK-IN-5 is an inhibitor of JAK extracted from patent US20170121327A1, compound example 283.
体内研究：
JAK-IN-5 (compound 1) (oral aspirate, 0.5 mg/mL, 50 μL ) inhibits STAT6 phosphorylation by 60% in IL-13-induced in lung tissue in a mouse model of pSTAT6 induction.JAK-IN-5 (compound 1) (oral aspirate, 0.1-1.0 mg/mL, 50 μL) inhibits 88% of BALF eosinophils in male C57 mice model of Alternaria alternata-induced eosinophilic inflammation of the lung.
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