产品
编 号:F029448
分子式:C3H7NO2
分子量:89.09
产品类型
结构图
CAS No: 107-97-1
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产品详情
生物活性:
Sarcosine (N-Methylglycine), an endogenous amino acid, is a competitive glycine transporter type I (GlyT1) inhibitor and N-methyl-D-aspartate (NMDA) receptor co-agonist. Sarcosine increases the glycine concentration, resulting in an indirect potentiation of the NMDA receptor. Sarcosine is commonly used for the research of schizophrenia.
体内研究:
Sarcosine (400-800mg/kg;ip) 显著提高电惊厥的阈值。Animal Model:Albino Swiss mice weighing (25-30 g)
Dosage:100 mg/kg, 200 mg/kg, 400 mg/kg, 800 mg/kg
Administration:Intraperitoneal injection
Result:Elevated the seizure threshold at doses of 400 mg/kg and 800 mg/kg in the MEST test in mice.