产品
编 号：F029428
分子式：C3H7NO2
分子量：89.09
分子式：C3H7NO2
分子量：89.09
产品类型
规格
价格
是否有货
500mg
400
In-stock
结构图
CAS No: 107-95-9
产品详情
生物活性：
β-Alanine is a non-essential amino acid that is shown to be metabolized into carnosine, which functions as an intracellular buffer.
体外研究：
Cells treated with β-alanine display significantly suppressed basal and peak ECAR (aerobic glycolysis), with simultaneous increase in glucose transporter 1 (GLUT1). Additionally, cells treated with β-alanine exhibit significantly reduced basal and peak OCR (oxidative metabolism), which is accompanied by reduction in mitochondrial content with subsequent suppression of genes which promote mitochondrial biosynthesis. Suppression of glycolytic and oxidative metabolism by β-alanine results in the reduction of total metabolic rate, although cell viability is not affected.β-alanine is shown to reduce both cell migration and proliferation without acting in a cytotoxic fashion. Moreover, β-alanine significantly increases malignant cell sensitivity to doxorubicin, suggesting a potential role as a co-therapeutic agent.
β-Alanine is a non-essential amino acid that is shown to be metabolized into carnosine, which functions as an intracellular buffer.
体外研究：
Cells treated with β-alanine display significantly suppressed basal and peak ECAR (aerobic glycolysis), with simultaneous increase in glucose transporter 1 (GLUT1). Additionally, cells treated with β-alanine exhibit significantly reduced basal and peak OCR (oxidative metabolism), which is accompanied by reduction in mitochondrial content with subsequent suppression of genes which promote mitochondrial biosynthesis. Suppression of glycolytic and oxidative metabolism by β-alanine results in the reduction of total metabolic rate, although cell viability is not affected.β-alanine is shown to reduce both cell migration and proliferation without acting in a cytotoxic fashion. Moreover, β-alanine significantly increases malignant cell sensitivity to doxorubicin, suggesting a potential role as a co-therapeutic agent.
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