产品
编 号:F255694
分子式:C23H29Cl2N3O
分子量:434.4
产品类型
结构图
CAS No: 2089293-61-6
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产品详情
生物活性:
NAcM-OPT is an orally bioavailable cullin neddylation 1 (DCN1) inhibitor, which potently inhibits the DCN1-UBE2M interaction.
体外研究:
NAcM-OPT (Compound 67) is orally bioavailable, well tolerated in mice, and currently used to study the effects of acute pharmacologic inhibition of the DCN1-UBE2M interaction on the NEDD8/CUL pathway.