产品
编 号：F255558
分子式：C26H19FO5S
分子量：462.49
分子式：C26H19FO5S
分子量：462.49
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
询价
1mg
询价
询价
5mg
询价
询价
10mg
询价
询价
结构图
CAS No: 2088518-51-6
产品详情
生物活性：
Rintodestrant (G1T48) is an orally active, non-steroidal and selective estrogen receptor degrader. Rintodestrant (G1T48) is also a CDK4/6 inhibitor.
体内研究：
Rintodestrant (G1T48, 30 or 100 mg/kg) inhibits estrogen signaling in endocrine-resistant breast cancer models.Animal Model:MCF7 xenograft tumors.
Dosage:30 or 100 mg/kg.
Administration:P.O. daily for 28 days.
Result:Demonstrated dose-dependent inhibition of TamR tumor growth.
体外研究：
Rintodestrant (G1T48) is a potent and efficacious inhibitor of estrogen-mediated transcription and proliferation in ER-positive breast cancer cells, similar to the pure antiestrogen fulvestrant.Rintodestrant (G1T48) selectively inhibits the growth of ER-positive, but not ER-negative, breast cancer cells.
Rintodestrant (G1T48) is an orally active, non-steroidal and selective estrogen receptor degrader. Rintodestrant (G1T48) is also a CDK4/6 inhibitor.
体内研究：
Rintodestrant (G1T48, 30 or 100 mg/kg) inhibits estrogen signaling in endocrine-resistant breast cancer models.Animal Model:MCF7 xenograft tumors.
Dosage:30 or 100 mg/kg.
Administration:P.O. daily for 28 days.
Result:Demonstrated dose-dependent inhibition of TamR tumor growth.
体外研究：
Rintodestrant (G1T48) is a potent and efficacious inhibitor of estrogen-mediated transcription and proliferation in ER-positive breast cancer cells, similar to the pure antiestrogen fulvestrant.Rintodestrant (G1T48) selectively inhibits the growth of ER-positive, but not ER-negative, breast cancer cells.
产品资料
Copyright©2015-2024 沪ICP备2022026524号-1
沪公网安备