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编 号:F254225
分子式:C16H8N2O3
分子量:276.25
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10mM*1mL in DMSO
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1mg
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2mg
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5mg
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10mg
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25mg
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50mg
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100mg
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生物活性:
SJB3-019A is a potent and novel USP1 inhibitor, 5 times more potent than SJB2-043 in promoting ID1 degradation and cytoxicity in K562 cells with IC50 of 0.0781 μM.

体外研究:
SJB3-019A (IC50=0.0781 μM) is 5 times more potent than SJB2-043 in promoting ID1 degradation and cytoxicity in K562 cells. SJB3-019A increases the levels of Ub-FANCD2 and Ub-PCNA, and decreases the HR activity.
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