产品
编 号:F252923
分子式:C18H18Cl2N2O
分子量:349.25
产品类型
结构图
CAS No: 2059904-66-2
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产品详情
生物活性:
BPR1M97 is a dual-acting mu opioid receptor (MOP) and nociceptin-orphanin FQ peptide (NOP) receptor agonist with Ki values of 1.8 and 4.2 nM, respectively. BPR1M97 shows high potency and blood-brain barrier penetration, and produces potent antinociceptive effects.
体内研究:
BPR1M97 (1.8 mg/kg; s.c.; once) demonstrates antinociception in a murine model of cancer pain.Animal Model:Male wild-type C57BL/6 mice (25-30?g)
Dosage:1.8 mg/kg
Administration:Subcutaneous injection (s.c.); once
Result:Demonstrated antinociception in a murine model of cancer pain.