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编 号：F251132
分子式：C24H26Cl2N2O
分子量：429.38
分子式：C24H26Cl2N2O
分子量：429.38
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CAS No: 204069-50-1
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生物活性：
RTI 336 is a phenyltropane analog, as well as a potent and selective dopamine transporter (DAT) inhibitor. RTI 336 inhibits addictive agent induced locomotor activity and self-administration in Lewis rats. RTI 336 exhibits inhibitory effects depending on inherent NAc DAT levels.
体内研究：
RTI 336（3 mg/kg；皮下注射；30 分钟预处理）显著减少 Lewis 大鼠对成瘾剂的输注次数。RTI 336（3 毫克/千克；腹腔注射；30 分钟预处理）降低 Lewis 大鼠中由成瘾剂诱导的反应率（杠杆按压/秒）。
RTI 336 is a phenyltropane analog, as well as a potent and selective dopamine transporter (DAT) inhibitor. RTI 336 inhibits addictive agent induced locomotor activity and self-administration in Lewis rats. RTI 336 exhibits inhibitory effects depending on inherent NAc DAT levels.
体内研究：
RTI 336（3 mg/kg；皮下注射；30 分钟预处理）显著减少 Lewis 大鼠对成瘾剂的输注次数。RTI 336（3 毫克/千克；腹腔注射；30 分钟预处理）降低 Lewis 大鼠中由成瘾剂诱导的反应率（杠杆按压/秒）。
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