产品
编 号：F250267
分子式：C21H36N4O8
分子量：472.53
分子式：C21H36N4O8
分子量：472.53
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
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1mg
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5mg
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10mg
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25mg
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50mg
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100mg
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结构图
CAS No: 203120-46-1
产品详情
生物活性：
Laninamivir octanoate (CS-8958), a proagent of Laninamivir, is a long-acting neuraminidase (NA) inhibitor with anti-influenza virus activity. Laninamivir octanoate shows anti-influenza activity against Oseltamivir-resistant viruses, and also against the pandemic influenza viruses.
体内研究：
Laninamivir octanoate (CS-8958; 95 μg/kg; intranasal administration; three dose; at 4 h before and 4 h and 17 h postinfection) treatment shows significantly life-prolonging effect in infected model.Animal Model:Female BALB/c mice (5-6 weeks old) infected with influenza A virus A/PR/8/34
Dosage:0.2 μmol/kg (95 μg/kg)
Administration:Intranasal administration; three dose; at 4 h before and 4 h and 17 h postinfection
Result:Showed life-prolonging effect in infected model.
体外研究：
Laninamivir octanoate (CS-8958) shows inhibitory activity with an IC50 of 631-1170 nM, 39.2-221 nM and 128 nM to the H1N1 viruses strains, H3N2 viruses strains and H2N2 (A/Singapore/1/57) virus, respectively.
Laninamivir octanoate (CS-8958), a proagent of Laninamivir, is a long-acting neuraminidase (NA) inhibitor with anti-influenza virus activity. Laninamivir octanoate shows anti-influenza activity against Oseltamivir-resistant viruses, and also against the pandemic influenza viruses.
体内研究：
Laninamivir octanoate (CS-8958; 95 μg/kg; intranasal administration; three dose; at 4 h before and 4 h and 17 h postinfection) treatment shows significantly life-prolonging effect in infected model.Animal Model:Female BALB/c mice (5-6 weeks old) infected with influenza A virus A/PR/8/34
Dosage:0.2 μmol/kg (95 μg/kg)
Administration:Intranasal administration; three dose; at 4 h before and 4 h and 17 h postinfection
Result:Showed life-prolonging effect in infected model.
体外研究：
Laninamivir octanoate (CS-8958) shows inhibitory activity with an IC50 of 631-1170 nM, 39.2-221 nM and 128 nM to the H1N1 viruses strains, H3N2 viruses strains and H2N2 (A/Singapore/1/57) virus, respectively.
产品资料
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