产品
编 号：F249504
分子式：C21H20O12
分子量：464.38
分子式：C21H20O12
分子量：464.38
产品类型
规格
价格
是否有货
1mg
询价
询价
5mg
询价
询价
10mg
询价
询价
结构图
CAS No: 20229-56-5
产品详情
生物活性：
Spiraeoside, an orally active natural compound, exerts antioxidant activity, inhibits reactive oxygen species (ROS) and malondialdehyde production. Spiraeoside possesses antiallergic, anti-inflammatory and antitumor activities.
体内研究：
Spiraeoside (50 mg/kg, p.o.) shows ulcer preventive ability.Animal Model:Male Wistar rats (6-8 weeks old).
Dosage:50 mg/kg.
Administration:Oral gavage an hour before inducing the lesions.
Result:Decreased severity of the formed lesions.
体外研究：
Spiraeoside elevates HG stimulation-caused the decrease in the expression levels of p-Akt, nuclear Nrf2, and HO-1 in AC16 cells (the effects of Spiraeoside are reversedby LY294002). Spiraeoside protects AC16 cells against HG-induced oxidative stress, cell injury, and apoptosis. Spiraeoside activates the PI3K/Akt/Nrf2 pathway in AC16 cells on exposure to HG.Spiraeoside protects AC16 cells against HG-induced apoptosis through the PI3K/Akt/Nrf2 pathway.
Spiraeoside, an orally active natural compound, exerts antioxidant activity, inhibits reactive oxygen species (ROS) and malondialdehyde production. Spiraeoside possesses antiallergic, anti-inflammatory and antitumor activities.
体内研究：
Spiraeoside (50 mg/kg, p.o.) shows ulcer preventive ability.Animal Model:Male Wistar rats (6-8 weeks old).
Dosage:50 mg/kg.
Administration:Oral gavage an hour before inducing the lesions.
Result:Decreased severity of the formed lesions.
体外研究：
Spiraeoside elevates HG stimulation-caused the decrease in the expression levels of p-Akt, nuclear Nrf2, and HO-1 in AC16 cells (the effects of Spiraeoside are reversedby LY294002). Spiraeoside protects AC16 cells against HG-induced oxidative stress, cell injury, and apoptosis. Spiraeoside activates the PI3K/Akt/Nrf2 pathway in AC16 cells on exposure to HG.Spiraeoside protects AC16 cells against HG-induced apoptosis through the PI3K/Akt/Nrf2 pathway.
产品资料
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