产品
编 号：F249494
分子式：C4H4FN3O
分子量：129.09
分子式：C4H4FN3O
分子量：129.09
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
询价
500mg
280
In-stock
1g
360
In-stock
5g
824
In-stock
结构图
CAS No: 2022-85-7
产品详情
生物活性：
Flucytosine (5-Fluorocytosine) is an antifungal compound with oral activity. Flucytosine is a widely used cytotoxic drug that, after further metabolism, produces fluorinated ribonucleotides and deoxyribonucleotides, inhibits DNA and protein synthesis, and has multiple effects such as inhibiting candida and candida neoplasm infection and producies cytotoxicity to cancer cells.
体内研究：
Flucytosine (500 mg/kg/天, 静脉注射, 持续 7 天) 可有效降低 CD-hMSC 小鼠的肿瘤体积和重量。Flucytosine (50, 75 mg/kg/天, 灌胃, 3-30 天) 联合伊曲康唑 (HY-17514) 可有效抑制仓鼠隐球菌感染。Animal Model:CD-hMSC mice
Dosage:500 mg/kg
Administration:i.v. for 7 days
Result:Inhibited tumor volume and bodyweight.
体外研究：
Flucytosine 在转染 CD 基因的 hMSC (CD-hMSC) 体系中有效地将 5-FC 转化为 5-FU，显示出抗癌治疗潜力。
Flucytosine (5-Fluorocytosine) is an antifungal compound with oral activity. Flucytosine is a widely used cytotoxic drug that, after further metabolism, produces fluorinated ribonucleotides and deoxyribonucleotides, inhibits DNA and protein synthesis, and has multiple effects such as inhibiting candida and candida neoplasm infection and producies cytotoxicity to cancer cells.
体内研究：
Flucytosine (500 mg/kg/天, 静脉注射, 持续 7 天) 可有效降低 CD-hMSC 小鼠的肿瘤体积和重量。Flucytosine (50, 75 mg/kg/天, 灌胃, 3-30 天) 联合伊曲康唑 (HY-17514) 可有效抑制仓鼠隐球菌感染。Animal Model:CD-hMSC mice
Dosage:500 mg/kg
Administration:i.v. for 7 days
Result:Inhibited tumor volume and bodyweight.
体外研究：
Flucytosine 在转染 CD 基因的 hMSC (CD-hMSC) 体系中有效地将 5-FC 转化为 5-FU，显示出抗癌治疗潜力。
产品资料
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