产品
编 号：F248629
分子式：C25H31NO4
分子量：409.52
分子式：C25H31NO4
分子量：409.52
产品类型
规格
价格
是否有货
1mg
询价
询价
5mg
询价
询价
10mg
询价
询价
25mg
询价
询价
50mg
询价
询价
结构图
CAS No: 201216-39-9
产品详情
生物活性：
4-PPBP maleate is a potent σ 1 receptor ligand and agonist. 4-PPBP maleate is a non-competitive, selective NR1a/2B NMDA receptors (expressed in Xenopus oocytes) antagonist. 4-PPBP maleate provides neuroprotection.
体内研究：
4-PPBP maleate (1 μmol/kg; i.v.) decreases brain injury after transient focal ischemia in rats.Animal Model:Male rats weighing 300 to 385 g (Transient focal ischemia model)
Dosage:1 μmol/kg
Administration:Per hour by continuous intravenous infusion starting 1 hour after the initiation of ischemia and continuing through 22 hours of reperfusion.
Result:Decreased brain injury after transient focal ischemia in rats.
体外研究：
4-PPBP maleate elicits ERK1/2 phosphorylation in primary neurons.
4-PPBP maleate is a potent σ 1 receptor ligand and agonist. 4-PPBP maleate is a non-competitive, selective NR1a/2B NMDA receptors (expressed in Xenopus oocytes) antagonist. 4-PPBP maleate provides neuroprotection.
体内研究：
4-PPBP maleate (1 μmol/kg; i.v.) decreases brain injury after transient focal ischemia in rats.Animal Model:Male rats weighing 300 to 385 g (Transient focal ischemia model)
Dosage:1 μmol/kg
Administration:Per hour by continuous intravenous infusion starting 1 hour after the initiation of ischemia and continuing through 22 hours of reperfusion.
Result:Decreased brain injury after transient focal ischemia in rats.
体外研究：
4-PPBP maleate elicits ERK1/2 phosphorylation in primary neurons.
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