产品
编 号：F247557
分子式：C23H21NO5
分子量：391.42
分子式：C23H21NO5
分子量：391.42
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
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5mg
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10mg
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25mg
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50mg
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100mg
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结构图
CAS No: 200189-97-5
产品详情
生物活性：
Omigapil maleate, an orally bioavailable GAPDH nitrosylation inhibitor, abrogates Aβ1-42-induced tau acetylation, memory impairment, and locomotor dysfunction in mice. Omigapil maleate has the potential for the research of Alzheimer's disease. Omigapil maleate (CGP3446B maleate) is a apoptosis inhibitor. Omigapil maleate can be used for the research of congenital muscular dystrophy (CMD). Omigapil (maleate) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
体内研究：
用 Omigapil maleate (0.1 mg/kg) 处理小鼠可改善肌肉再生并增加力量。Animal Model:12-week-old dyW/ mag mice
Dosage:0.1 mg/kg
Administration:For the first week of drug treatment, administered once daily by intraperitoneal injection. After weaning (3 weeks of age), applied once daily by oral gavage.
Result:Reduced the muscle fibre loss. Many of the functional parameters were significantly improved by omigapil.
Omigapil maleate, an orally bioavailable GAPDH nitrosylation inhibitor, abrogates Aβ1-42-induced tau acetylation, memory impairment, and locomotor dysfunction in mice. Omigapil maleate has the potential for the research of Alzheimer's disease. Omigapil maleate (CGP3446B maleate) is a apoptosis inhibitor. Omigapil maleate can be used for the research of congenital muscular dystrophy (CMD). Omigapil (maleate) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
体内研究：
用 Omigapil maleate (0.1 mg/kg) 处理小鼠可改善肌肉再生并增加力量。Animal Model:12-week-old dyW/ mag mice
Dosage:0.1 mg/kg
Administration:For the first week of drug treatment, administered once daily by intraperitoneal injection. After weaning (3 weeks of age), applied once daily by oral gavage.
Result:Reduced the muscle fibre loss. Many of the functional parameters were significantly improved by omigapil.
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