产品
编 号：F247214
分子式：C12H21N
分子量：179.3
分子式：C12H21N
分子量：179.3
产品类型
规格
价格
是否有货
5mg
询价
询价
结构图
CAS No: 19982-08-2
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生物活性：
Memantine is an orally active, noncompetitive N-methyl-D-aspartate receptor (NMDAR) antagonist. Memantine can be used for the research of moderate-to-severe Alzheimer's disease (AD).
体内研究：
Memantine (1, 5 and 10, 15 mg/kg; i.p.; daily for 15-20 days) significantly decreased the large LTP recorded in hippocampal slices from aged animals.Memantine (1-3 mg/kg; per os (p.o.)) for 14 days significantly improves depressive-like behaviors in olfactory bulbectomized (OBX) mice, as assessed using the tail-suspension and forced-swim tests.Animal Model:Male Wistar rats
Dosage:1, 5 and 10, 15 mg/kg
Administration:i.p.; daily for 15-20 days
Result:Significantly decreased the large LTP recorded in hippocampal slices from aged animals.
Memantine is an orally active, noncompetitive N-methyl-D-aspartate receptor (NMDAR) antagonist. Memantine can be used for the research of moderate-to-severe Alzheimer's disease (AD).
体内研究：
Memantine (1, 5 and 10, 15 mg/kg; i.p.; daily for 15-20 days) significantly decreased the large LTP recorded in hippocampal slices from aged animals.Memantine (1-3 mg/kg; per os (p.o.)) for 14 days significantly improves depressive-like behaviors in olfactory bulbectomized (OBX) mice, as assessed using the tail-suspension and forced-swim tests.Animal Model:Male Wistar rats
Dosage:1, 5 and 10, 15 mg/kg
Administration:i.p.; daily for 15-20 days
Result:Significantly decreased the large LTP recorded in hippocampal slices from aged animals.
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