产品
编 号:F246218
分子式:C24H30N4O5
分子量:454.52
产品类型
结构图
CAS No: 19875-60-6
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产品详情
生物活性:
Lisuride (maleate) is a potent agonist of dopamine with a probably direct action on dopaminergic receptors. Lisuride (maleate) is an ergot derivative. Lisuride (maleate) releases the premenstrual mastalgia without significant side effects.
体内研究:
Lisuride (maleate) (0.78 and 3.13 mg/kg; i.p.; p.o.) is 3-4 times more potent on i.p. than on p.o. .Lisuride (maleate) (0.78-3.13 mg/kg; i.p.) antagonizes the motor depression and hypothermia induced by reserpine.Lisuride (maleate) (0.78-3.13 mg/kg; i.p.) is about as effective as apomorphine and D-amphetamine and causes significant hypothermia measured after dosages as low as 0.10 mg/kg i.p..Animal Model:NMRI mice (18-25 g)
Dosage:0.78 and 3.13 mg/kg
Administration:i.p., p.o.
Result:Been 3-4 times more potent on i.p. than on p.o..