产品
编 号:F002925
分子式:C27H28N4O5S
分子量:520.6
产品类型
结构图
CAS No: 1005549-94-9
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生物活性:
Taprenepag isopropyl is a highly selective EP2 receptor agonist.
体内研究:
Taprenepag isopropyl is a highly selective EP2 receptor agonist. Intraocular pressure (IOP) in the left, vehicle-dosed eye typically remains within the normal range. In the right (Taprenepag isopropyl-dosed) eye, IOP is reduced in all dose groups. In the high-dose group, IOP is reduced to the extent that it cannot be measured (<4mm Hg) on Days 22 and 29. There are no clinical signs or changes in body weight observed with any dose of Taprenepag isopropyl administration, and noocular findings occur for animals in the low-dose group (0.75 mg/day).