产品
编 号：F245101
分子式：C20H14ClN
分子量：303.78
分子式：C20H14ClN
分子量：303.78
产品类型
规格
价格
是否有货
1mg
询价
询价
5mg
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10mg
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25mg
询价
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50mg
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100mg
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结构图
CAS No: 197525-99-8
产品详情
生物活性：
TRAM-39 is a selective blocker of intermediate conductance Ca2+-activated K+ (IKCa) channels. TRAM-39 inhibits KCa3.1 channel with an IC50 value of 60 nM. TRAM-39 can be used for the research of ataxia, epilepsy, memory disorders, schizophrenia and Parkinson’s disease.
体内研究：
TRAM-39 (1 μM; adds to the perfusate) fully blocks all IKCa channels in multicellular preparations.
体外研究：
TRAM-39 (1 μM) reduces the peak amplitude of gKCa2 in sympathetic LAH neurons (mean percentage change 56%) in BAE cells.TRAM-39 (200 nM) diminishes lipopolysaccharide (LPS)-induced cryptdin release from paneth cells.
TRAM-39 is a selective blocker of intermediate conductance Ca2+-activated K+ (IKCa) channels. TRAM-39 inhibits KCa3.1 channel with an IC50 value of 60 nM. TRAM-39 can be used for the research of ataxia, epilepsy, memory disorders, schizophrenia and Parkinson’s disease.
体内研究：
TRAM-39 (1 μM; adds to the perfusate) fully blocks all IKCa channels in multicellular preparations.
体外研究：
TRAM-39 (1 μM) reduces the peak amplitude of gKCa2 in sympathetic LAH neurons (mean percentage change 56%) in BAE cells.TRAM-39 (200 nM) diminishes lipopolysaccharide (LPS)-induced cryptdin release from paneth cells.
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