产品
编 号:F242875
分子式:C13H8N2O2S
分子量:256.28
产品类型
结构图
CAS No: 1954650-11-3
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生物活性:
JMS-053 is a potent, selective and reversible PTP4A inhibitor, with IC50s of 29.1 nM, 48.0 nM, 34.7 nM, 92.6 nM, and 207.6 nM for PTP4A1, PTP4A2, PTP4A3, CDC25B, and DUSP3, respectively. JMS-053 can inhibit cancer cell migration and spheroid growth in vitro, attenuate in vivo ovarian tumor growth.