产品
编 号：F242635
分子式：C18H30N2O2S
分子量：338.51
分子式：C18H30N2O2S
分子量：338.51
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
询价
1mg
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5mg
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10mg
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25mg
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50mg
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结构图
CAS No: 195199-95-2
产品详情
生物活性：
SB 258719 is a selective 5-HT7 receptor antagonist with high affinity (pKi=7.5) for the receptor. SB 258719 can be used for the research of cancer and neurological disease.
体内研究：
SB 258719 (5-20 mg/kg; i.p.) significantly attenuates the 5-CT-induced hypothermia.Animal Model:Male Swiss Webster mice (20-25 g).
Dosage:5-20 mg/kg
Administration:I.p.
Result:Significantly attenuated the 5-CT-induced hypothermia.
体外研究：
SB 258719 (1, 3 and 10 μM; HEK 293 cells) produces a concentration-related rightward-shift of the 5-CT concentration-response curve with no signifcant alteration in the maximal response to 5-CT.
SB 258719 is a selective 5-HT7 receptor antagonist with high affinity (pKi=7.5) for the receptor. SB 258719 can be used for the research of cancer and neurological disease.
体内研究：
SB 258719 (5-20 mg/kg; i.p.) significantly attenuates the 5-CT-induced hypothermia.Animal Model:Male Swiss Webster mice (20-25 g).
Dosage:5-20 mg/kg
Administration:I.p.
Result:Significantly attenuated the 5-CT-induced hypothermia.
体外研究：
SB 258719 (1, 3 and 10 μM; HEK 293 cells) produces a concentration-related rightward-shift of the 5-CT concentration-response curve with no signifcant alteration in the maximal response to 5-CT.
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