产品
编 号：F241869
分子式：C23H20N2O5
分子量：404.42
分子式：C23H20N2O5
分子量：404.42
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
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1mg
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5mg
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10mg
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25mg
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结构图
CAS No: 194414-69-2
产品详情
生物活性：
Camptothecin-20(S)-O-propionate (CZ48), the C20-propionate ester of CPT, is a highly effective anticancer agent. Camptothecin-20(S)-O-propionate (CZ48) is a topoisomerase-Ι inhibitor.
体内研究：
Camptothecin-20(S)-O-propionate (CZ48, gavage, 100 to 2000 mg/kg/day) exhibits anti-tumor activity in CLO-breast carcinoma (100 mg/kg) and PC3-prostate carcinoma (1000 mg/kg) models in mice.Animal Model:A tumor xenograft growing in a nude mouse (size, ～1 cm3).
Dosage:100-1000 mg/kg/day.
Administration:Oral gavage, for 2, 4 and 6 days, respectively.
Result:Exhibited anti-tumor effect.
Camptothecin-20(S)-O-propionate (CZ48), the C20-propionate ester of CPT, is a highly effective anticancer agent. Camptothecin-20(S)-O-propionate (CZ48) is a topoisomerase-Ι inhibitor.
体内研究：
Camptothecin-20(S)-O-propionate (CZ48, gavage, 100 to 2000 mg/kg/day) exhibits anti-tumor activity in CLO-breast carcinoma (100 mg/kg) and PC3-prostate carcinoma (1000 mg/kg) models in mice.Animal Model:A tumor xenograft growing in a nude mouse (size, ～1 cm3).
Dosage:100-1000 mg/kg/day.
Administration:Oral gavage, for 2, 4 and 6 days, respectively.
Result:Exhibited anti-tumor effect.
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