产品
编 号:F027045
分子式:C32H46O7
分子量:542.7
产品类型
结构图
CAS No: 107140-30-7
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生物活性:
Kazusamycin B is an antibiotic that could be isolated from the fermentation broth of Streptomyces sp. No. 81-484. Kazusamycin B inhibits cell growth and arrests cell cycle at G1 phase. Kazusamycin B can be used in research of cancer.
体外研究:
Kazusamycin B (PD 124895; 5 ng/mL; 24 h; 1210 cells) 具有时间依赖性的细胞毒性,使细胞周期停滞在 G1 期。Kazusamycin B (5-50 ng/mL; 0-6 h; 1210 cells) 适度抑制 RNA 合成,但特异性抑制 2 小时。