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编 号:F240481
分子式:C21H28ClNO3
分子量:377.9
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10mM*1mL in DMSO
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1mg
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5mg
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10mg
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25mg
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50mg
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100mg
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生物活性:
Co 101244 (PD 174494) hydrochloride is a NR2B-containing NMDA receptor antagonist.

体内研究:
Co 101244 (0.1, 1 mg/kg s.c.) displayed antidyskinetic effects (67 and 71% reduction, respectively) while sparing levodopa motor benefit.

体外研究:
Co 101244 effectively reduces NMDA-evoked Ca2+ elevations while enhancing neuroprotection.
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