产品
编 号:F240481
分子式:C21H28ClNO3
分子量:377.9
产品类型
结构图
CAS No: 193356-17-1
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产品详情
生物活性:
Co 101244 (PD 174494) hydrochloride is a NR2B-containing NMDA receptor antagonist.
体内研究:
Co 101244 (0.1, 1 mg/kg s.c.) displayed antidyskinetic effects (67 and 71% reduction, respectively) while sparing levodopa motor benefit.
体外研究:
Co 101244 effectively reduces NMDA-evoked Ca2+ elevations while enhancing neuroprotection.