产品
编 号：F239302
分子式：C24H20ClF2N3O2
分子量：455.88
分子式：C24H20ClF2N3O2
分子量：455.88
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CAS No: 1922099-21-5
产品详情
生物活性：
CCG-232601 (compound 8f) is a potent and orally active Rho/MRTF/SRF transcriptional pathway inhibitor. CCG-232601 inhibits the development of Bleomycin-induced dermal fibrosis in mice. CCG-232601 has the potential for the research of antifibrotic for systemic scleroderma.
体内研究：
CCG-232601 (50 mg/kg; i.g.; intracutaneous injections of bleomycin; daily for 14 days) inhibits bleomycin-induced skin fibrosis in mice.
体外研究：
CCG-232601 inhibits SRE.L activity with an IC50 of 0.55 μM.
CCG-232601 (compound 8f) is a potent and orally active Rho/MRTF/SRF transcriptional pathway inhibitor. CCG-232601 inhibits the development of Bleomycin-induced dermal fibrosis in mice. CCG-232601 has the potential for the research of antifibrotic for systemic scleroderma.
体内研究：
CCG-232601 (50 mg/kg; i.g.; intracutaneous injections of bleomycin; daily for 14 days) inhibits bleomycin-induced skin fibrosis in mice.
体外研究：
CCG-232601 inhibits SRE.L activity with an IC50 of 0.55 μM.
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