产品
编 号：F238537
分子式：C45H73NO16
分子量：884.06
分子式：C45H73NO16
分子量：884.06
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
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1mg
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5mg
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10mg
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20mg
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结构图
CAS No: 19121-58-5
产品详情
生物活性：
Solasonine is a ferroptosis inducer which can be isolated from Solanum melongena that has anti-infection, anti-cancer, and neurogenesis promoting properties. Solasonine promotes ferroptosis of HCC cells via destruction of the glutathione redox system induced by inhibiting GPX4, and can be used for cancer research.
体外研究：
Solasonine (2.5-50 ng/mL, 24 h) 剂量依赖性地抑制 HepG2 和 HepRG 的细胞活力，IC50约为15 ng/mL。Solasonine (15 ng/mL, 24 h) 显著增加 HepG2 和 HepRG 细胞的凋亡比例，从约 4% 增加到 20% 以上。
Solasonine is a ferroptosis inducer which can be isolated from Solanum melongena that has anti-infection, anti-cancer, and neurogenesis promoting properties. Solasonine promotes ferroptosis of HCC cells via destruction of the glutathione redox system induced by inhibiting GPX4, and can be used for cancer research.
体外研究：
Solasonine (2.5-50 ng/mL, 24 h) 剂量依赖性地抑制 HepG2 和 HepRG 的细胞活力，IC50约为15 ng/mL。Solasonine (15 ng/mL, 24 h) 显著增加 HepG2 和 HepRG 细胞的凋亡比例，从约 4% 增加到 20% 以上。
产品资料
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