产品
编 号：F238420
分子式：C18H16O6
分子量：328.32
分子式：C18H16O6
分子量：328.32
产品类型
规格
价格
是否有货
1mg
询价
询价
2mg
询价
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5mg
询价
询价
10mg
询价
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25mg
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结构图
CAS No: 19103-54-9
产品详情
生物活性：
Salvigenin is a natural polyphenolic compound, with neuroprotective effect. Salvigenin has antitumor cytotoxic and immunomodulatory properties. Salvigenin inhibits H2O2-induced cell apoptosis.
体内研究：
Salvigenin (0-9.68 μg/mouse/day; i.p.; 4 or 12 days) shows antitumor and immunomodulatory effects on tumor bearing mice.Animal Model:MCF-7 cell bearing inbred female Balb/c mice, aged from six to eight weeks
Dosage:3.65, 5.85 and 9.68 μg/mouse/day for four days or 12 days
Administration:Intraperitoneal injection
Result:Showed a significant increase in DTH response in a dose-dependent manner. Significantly decreased the rate of tumor growth, increased lymphocyte proliferation index, increased the level of IFN-γ and decreased IL-4 production. Exhibited a significant decrease of the splenic CD4+CD25+Foxp3+ T lymphocytes.
体外研究：
Salvigenin (0-100 μM, 3 h) protects SH-SY5Y cells against H2O2-induced cell death.Salvigenin (0-100 μM, 2 h) significantly reduces ROS generation, increases the glutathione level, declines the extent of cell apoptosis and increases autophagy in H2O2-exposed SH-SY5Y cells.
Salvigenin is a natural polyphenolic compound, with neuroprotective effect. Salvigenin has antitumor cytotoxic and immunomodulatory properties. Salvigenin inhibits H2O2-induced cell apoptosis.
体内研究：
Salvigenin (0-9.68 μg/mouse/day; i.p.; 4 or 12 days) shows antitumor and immunomodulatory effects on tumor bearing mice.Animal Model:MCF-7 cell bearing inbred female Balb/c mice, aged from six to eight weeks
Dosage:3.65, 5.85 and 9.68 μg/mouse/day for four days or 12 days
Administration:Intraperitoneal injection
Result:Showed a significant increase in DTH response in a dose-dependent manner. Significantly decreased the rate of tumor growth, increased lymphocyte proliferation index, increased the level of IFN-γ and decreased IL-4 production. Exhibited a significant decrease of the splenic CD4+CD25+Foxp3+ T lymphocytes.
体外研究：
Salvigenin (0-100 μM, 3 h) protects SH-SY5Y cells against H2O2-induced cell death.Salvigenin (0-100 μM, 2 h) significantly reduces ROS generation, increases the glutathione level, declines the extent of cell apoptosis and increases autophagy in H2O2-exposed SH-SY5Y cells.
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