产品
编 号：F026696
分子式：C18H22N2O5
分子量：346.38
分子式：C18H22N2O5
分子量：346.38
产品类型
规格
价格
是否有货
5mg
询价
询价
10mg
询价
询价
50mg
询价
询价
100mg
询价
询价
结构图
CAS No: 107008-28-6
产品详情
生物活性：
RU 24969 succinate is a 5-HT receptor agonist with Ki values of 0.38 and 2.5 nM for 5-HT1B and 5-HT1A, respectively. RU 24969 decreases fluid consumption and increases forward locomotion. RU 24969 succinate can be used for the research of neurological disease.
体内研究：
RU 24969 succinate (1 mg/kg 和 3 mg/kg；皮下注射，1 次) 增强成瘾剂诱导产生的作用。RU 24969 succinate (0.03-3.0 mg/kg；皮下注射，1 次) 剂量依赖性地减少水剥夺大鼠的水消耗。Animal Model:Male Wistar rats with cocaine injection
Dosage:1 and 3 mg/kg
Administration:Subcutaneous injection; 1 and 3 mg/kg, once
Result:Increased cocaine-induced elevation of nucleus accumbens (NAcc) dopamine DA levels and reduction of ventral tegmental area (VTA) GABA levels.
体外研究：
RU 24969 succinate (30 nM-1 μM) 抑制 K+ 诱发的氚外排，在 1 μM 浓度下 pD2 为 7.45。
RU 24969 succinate is a 5-HT receptor agonist with Ki values of 0.38 and 2.5 nM for 5-HT1B and 5-HT1A, respectively. RU 24969 decreases fluid consumption and increases forward locomotion. RU 24969 succinate can be used for the research of neurological disease.
体内研究：
RU 24969 succinate (1 mg/kg 和 3 mg/kg；皮下注射，1 次) 增强成瘾剂诱导产生的作用。RU 24969 succinate (0.03-3.0 mg/kg；皮下注射，1 次) 剂量依赖性地减少水剥夺大鼠的水消耗。Animal Model:Male Wistar rats with cocaine injection
Dosage:1 and 3 mg/kg
Administration:Subcutaneous injection; 1 and 3 mg/kg, once
Result:Increased cocaine-induced elevation of nucleus accumbens (NAcc) dopamine DA levels and reduction of ventral tegmental area (VTA) GABA levels.
体外研究：
RU 24969 succinate (30 nM-1 μM) 抑制 K+ 诱发的氚外排，在 1 μM 浓度下 pD2 为 7.45。
产品资料
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