产品
编 号：F237981
分子式：C22H20Cl2F2N6O3
分子量：525.34
分子式：C22H20Cl2F2N6O3
分子量：525.34
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
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1mg
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5mg
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10mg
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25mg
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50mg
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100mg
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结构图
CAS No: 1906919-67-2
产品详情
生物活性：
BAY-598 is selective small molecule inhibitor of SMYD2 with an IC50 of 27 nM.
体外研究：
BAY-598 treatment blocks in vitro methylation of MAPKAPK3 by SMYD2 but has no activity against the SMYD2-related KMT SMYD3. BAY-598 treatment reduces the growth of Kras;p53 mutant PDAC cells after 9 d in culture but has little impact on the growth of Kras;p53;Smyd2 mutant cells.
BAY-598 is selective small molecule inhibitor of SMYD2 with an IC50 of 27 nM.
体外研究：
BAY-598 treatment blocks in vitro methylation of MAPKAPK3 by SMYD2 but has no activity against the SMYD2-related KMT SMYD3. BAY-598 treatment reduces the growth of Kras;p53 mutant PDAC cells after 9 d in culture but has little impact on the growth of Kras;p53;Smyd2 mutant cells.
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