产品
编 号:F235957
分子式:C10H11N4O7P
分子量:330.19
产品类型
结构图
CAS No: 188696-80-2
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产品详情
生物活性:
Becampanel (AMP397) is the first competitive AMPA antagonist and an antiepileptic agent.
体内研究:
Becampanel is negative in the following in vivo studies, which includes the maximum tolerated doses of 320 mg/kg in mice and 2000 mg/kg in rats. Becampanel has no genotoxic potential in vivo.
体外研究:
Becampanel is negative in a mouse lymphoma tk assay, which includes a 24 h treatment without S9. A weak micronucleus induction in vitro is found at the highest concentrations tested in V79 cells with S9.