产品
编 号：F026414
分子式：C58H80Cl2N2O14
分子量：1100.17
分子式：C58H80Cl2N2O14
分子量：1100.17
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
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1mg
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5mg
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10mg
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25mg
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50mg
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100mg
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结构图
CAS No: 106861-44-3
产品详情
生物活性：
Mivacurium dichloride is a benzylisoquinoline derivative and is a short-acting non-depolarizing neuromuscular blocking agent and skeletal muscle relaxant. Mivacurium dichloride couples with the nAChR to reduce or inhibit the depolarizing effect of acetylcholine on the terminal disc of the muscle cell.
体内研究：
Mivacurium causes pseudo-allergic reactions in C57 wild-type mice by inducing mast cells to release histamine and a decrease in body temperature. Mivacurium is rapidly hydrolyzed in the plasma and has a short duration of action (< 10 min). Mivacurium has many advantages, such as a rapid effect, nonneurological toxicity and a lack of heart rate alteration.
体外研究：
Mivacurium induces LAD2 cell degranulation in a dose-dependent manner. Mivacurium stimulates intracellular Ca2+ influx in MRGPRX2-HEK293 cells but not in NC-HEK293 cells. Mivacurium induces the release of only low levels of mediators in LAD2 cells transfected with MRGPRX2-targeted small interfering siRNA.
Mivacurium dichloride is a benzylisoquinoline derivative and is a short-acting non-depolarizing neuromuscular blocking agent and skeletal muscle relaxant. Mivacurium dichloride couples with the nAChR to reduce or inhibit the depolarizing effect of acetylcholine on the terminal disc of the muscle cell.
体内研究：
Mivacurium causes pseudo-allergic reactions in C57 wild-type mice by inducing mast cells to release histamine and a decrease in body temperature. Mivacurium is rapidly hydrolyzed in the plasma and has a short duration of action (< 10 min). Mivacurium has many advantages, such as a rapid effect, nonneurological toxicity and a lack of heart rate alteration.
体外研究：
Mivacurium induces LAD2 cell degranulation in a dose-dependent manner. Mivacurium stimulates intracellular Ca2+ influx in MRGPRX2-HEK293 cells but not in NC-HEK293 cells. Mivacurium induces the release of only low levels of mediators in LAD2 cells transfected with MRGPRX2-targeted small interfering siRNA.
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