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编 号:F235499
分子式:C10H20ClNO4
分子量:253.72
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5mg
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10mg
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25mg
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50mg
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100mg
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生物活性:
Propionyl-DL-carnitine chloride is a carnitine derivative. Propionyl-DL-carnitine chloride can be used for the research of inflammation.

体内研究:
Propionyl-DL-carnitine chloride (2 mM/kg; p.o. once daily for 4 weeks) affects plasma and urine total carnitine concentrations of mice.Animal Model:Adult age-matched male C57BL/6 mice
Dosage:2 mM/kg
Administration:Oral gavage; 2 mM/kg/day for 4 weeks
Result:Increased plasma and urine total carnitine concentrations, but showed no effect on the skeletal muscle carnitine content of mice.

体外研究:
Propionyl-DL-carnitine chloride shows protection to beta-thalassaemic erythrocytes from oxidative stress.Propionyl-DL-carnitine chloride increases production of 14CO2 from [1-14C]pyruvate and increases the rate of formation of acetyl camitine from pyruvate.Propionyl-DL-carnitine chloride allows the endothelial cells to maintain their functionality and regulatory role on vessel activity for a longer time and decreases the formation of oxygen reactive species due to xanthine oxidase activity on hypoxanthine formed by adenine nucleotide catabolism.
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