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编 号:F232552
分子式:C27H23F3N4O
分子量:476.49
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CP-319340 free base is a microsomal triglyceride transfer protein (MTP) inhibitor.

体外研究:
Microsomal triglyceride transfer protein (MTP) and apolipoprotein B (ApoB) are necessary for lipoprotein assembly. MTP binds to ApoB with high affinity involving ionic interactions. MTP interacts at multiple sites in the N-terminal beta alpha structural domain of apoB.
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