产品
编 号:F231438
分子式:C13H17NO6
分子量:283.28
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5mg
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10mg
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25mg
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50mg
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生物活性:
PF-06761281 (Compound 4a) is a potent, orally active, partial selective sodium-coupled citrate transporter (NaCT or SLC13A5) inhibitor with IC50 values of 0.51, 13.2 and 14.1 μM against HEKNaCT, HEKNaDC1 and HEKNaDC3, respectively.

体外研究:
PF-06761281 (Compound 4a) inhibits citrate uptake with IC50 values of 0.12, 0.21 and 0.74 μM in rat, mouse and human Heps.
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