产品
编 号：F231287
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规格
价格
是否有货
1mg
询价
询价
5mg
询价
询价
结构图
CAS No: 185243-69-0
产品详情
生物活性：
Etanercept, a dimeric fusion protein that binds TNF, acts as a TNF inhibitor. Etanercept competitively inhibits the binding of both TNF-α and TNF-β to cell surface TNF receptors, rendering TNF biologically inactive. Etanercept shows efficacy against rheumatoid arthritis, juvenile idiopathic arthritis, and plaque psoriasis.
体内研究：
Etanercept (10 mg/kg; s.c.; every 3 days for 3 weeks) significantly decreases the mean arthritis scores and radiological score.Animal Model:Six-week-old male Lewis rats (adjuvant-induced arthritis (AIA) model)
Dosage:10 mg/kg
Administration:S.c.; every 3 days for 3 weeks
Result:Significantly decreased the mean arthritis scores; Significant decreased in radiological score at the end of the treatment period.
Etanercept, a dimeric fusion protein that binds TNF, acts as a TNF inhibitor. Etanercept competitively inhibits the binding of both TNF-α and TNF-β to cell surface TNF receptors, rendering TNF biologically inactive. Etanercept shows efficacy against rheumatoid arthritis, juvenile idiopathic arthritis, and plaque psoriasis.
体内研究：
Etanercept (10 mg/kg; s.c.; every 3 days for 3 weeks) significantly decreases the mean arthritis scores and radiological score.Animal Model:Six-week-old male Lewis rats (adjuvant-induced arthritis (AIA) model)
Dosage:10 mg/kg
Administration:S.c.; every 3 days for 3 weeks
Result:Significantly decreased the mean arthritis scores; Significant decreased in radiological score at the end of the treatment period.
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