产品
编 号：F230750
分子式：C31H28F2N4O3
分子量：542.58
分子式：C31H28F2N4O3
分子量：542.58
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CAS No: 1848233-57-7
产品详情
生物活性：
DH-376 is a potent diacylglycerol lipase inhibitor with pIC50 values of 8.6 and 8.9 for ABHD6 and DAGLα, respectively. DH-376 prevents fasting-induced refeeding of mice. DH-376 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
体内研究：
DH-376 (50 mg/kg; i.p.) 减少小鼠禁食诱导的再喂食。Animal Model:male C57Bl/6J mice
Dosage:50 mg/kg
Administration:intraperitoneal injection
Result:Inhibitd fasting-induced refeeding.
DH-376 is a potent diacylglycerol lipase inhibitor with pIC50 values of 8.6 and 8.9 for ABHD6 and DAGLα, respectively. DH-376 prevents fasting-induced refeeding of mice. DH-376 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
体内研究：
DH-376 (50 mg/kg; i.p.) 减少小鼠禁食诱导的再喂食。Animal Model:male C57Bl/6J mice
Dosage:50 mg/kg
Administration:intraperitoneal injection
Result:Inhibitd fasting-induced refeeding.
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