产品
编 号:F229530
分子式:C9H11ClN4O2
分子量:242.66
产品类型
结构图
CAS No: 183204-74-2
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产品详情
生物活性:
Tipiracil is a thymidine phosphorylase (TPase) inhibitor.
体外研究:
Tipiracil is an inhibitor of thymidine phosphorylase. Tipiracil increases trifluridine exposure by inhibiting its metabolism by thymidine phosphorylase. The combination of Trifluridine and Tipiracil is a new oral treatment for metastatic colorectal cancer. Tipiracil prevents degradation of FTD through a first-pass effect as a thymidine phosphorylase inhibitor.