产品
编 号：F227010
分子式：C28H29NO4S
分子量：475.6
分子式：C28H29NO4S
分子量：475.6
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CAS No: 182133-25-1
产品详情
生物活性：
Arzoxifene (LY353381) is an orally active selective estrogen receptor modulator with a fixed ring structure similar to raloxifene. Arzoxifene has minimal side effects with powerful antiestrogenic effects on breast cancer and endometrium, with equally strong favorable estrogenic effects on bone and lipid profile.
体内研究：
Arzoxifene inhibits MCF-7 breast cancer xenograft growth in oophorectomized athymic mice. Arzoxifene is reported to prevent body weight increase in oophorectomized rats.
体外研究：
Arzoxifene reduces estrogen receptor expression in endometrial cancer cell lines (ECC-1).
Arzoxifene (LY353381) is an orally active selective estrogen receptor modulator with a fixed ring structure similar to raloxifene. Arzoxifene has minimal side effects with powerful antiestrogenic effects on breast cancer and endometrium, with equally strong favorable estrogenic effects on bone and lipid profile.
体内研究：
Arzoxifene inhibits MCF-7 breast cancer xenograft growth in oophorectomized athymic mice. Arzoxifene is reported to prevent body weight increase in oophorectomized rats.
体外研究：
Arzoxifene reduces estrogen receptor expression in endometrial cancer cell lines (ECC-1).
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