产品
编 号：F225969
分子式：C22H17F4N3O2
分子量：431.38
分子式：C22H17F4N3O2
分子量：431.38
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
询价
5mg
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10mg
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25mg
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50mg
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结构图
CAS No: 181629-93-6
产品详情
生物活性：
SB228357 is a selective, potent and orall active 5-HT2C/2B receptor antagonist with pKi values of 6.9, 8.0 and 9.0 for 5-HT2A, 5-HT2B and 5-HT2C, respectively. SB228357 has antidepressant/anxiolytic effects.
体内研究：
SB228357 (0-10 mg/kg; oral administration; for 90 minutes; male Sprague Dawley rats) treatment significantly reverses Haloperidol-induced catalepsy.Animal Model:Male Sprague Dawley rats (200-250?g) injected with Haloperidol
Dosage:0 mg/kg, 0.32 mg/kg, 1 mg/kg, 3.2 mg/kg, 10 mg/kg
Administration:Oral administration; for 90 minutes
Result:Significantly reversed Haloperidol-induced catalepsy.
SB228357 is a selective, potent and orall active 5-HT2C/2B receptor antagonist with pKi values of 6.9, 8.0 and 9.0 for 5-HT2A, 5-HT2B and 5-HT2C, respectively. SB228357 has antidepressant/anxiolytic effects.
体内研究：
SB228357 (0-10 mg/kg; oral administration; for 90 minutes; male Sprague Dawley rats) treatment significantly reverses Haloperidol-induced catalepsy.Animal Model:Male Sprague Dawley rats (200-250?g) injected with Haloperidol
Dosage:0 mg/kg, 0.32 mg/kg, 1 mg/kg, 3.2 mg/kg, 10 mg/kg
Administration:Oral administration; for 90 minutes
Result:Significantly reversed Haloperidol-induced catalepsy.
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