产品
编 号：F224655
分子式：C16H18ClNO3S2
分子量：371.9
分子式：C16H18ClNO3S2
分子量：371.9
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CAS No: 1807453-83-3
产品详情
生物活性：
ND-336 is a selective inhibitor of matrix metalloproteinase (MMP)-2, MMP-9, and MMP-14, with Kis of 85, 150, and 120 nM, respectively. ND-336 accelerates diabetic wound healing in mice by lowering inflammation and by enhancing angiogenesis and re-epithelialization of the wound.
体内研究：
ND-336 accelerates diabetic wound healing by decreasing inflammation and by enhancing angiogenesis and re-epithelialization of the wound, thus reversing the pathological condition.ND-336 (0.05-0.01 mg; topical application; daily for 14 day) accelerates diabetic wound healing.Animal Model:Female diabetic db/db mice
Dosage:0.05, 0.025, and 0.01 mg
Administration:Topical application; daily for 14 day
Result:Healed 1.2- to 1.6-fold faster than those treated with ND-322 than those treated with vehicle.
ND-336 is a selective inhibitor of matrix metalloproteinase (MMP)-2, MMP-9, and MMP-14, with Kis of 85, 150, and 120 nM, respectively. ND-336 accelerates diabetic wound healing in mice by lowering inflammation and by enhancing angiogenesis and re-epithelialization of the wound.
体内研究：
ND-336 accelerates diabetic wound healing by decreasing inflammation and by enhancing angiogenesis and re-epithelialization of the wound, thus reversing the pathological condition.ND-336 (0.05-0.01 mg; topical application; daily for 14 day) accelerates diabetic wound healing.Animal Model:Female diabetic db/db mice
Dosage:0.05, 0.025, and 0.01 mg
Administration:Topical application; daily for 14 day
Result:Healed 1.2- to 1.6-fold faster than those treated with ND-322 than those treated with vehicle.
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