产品
编 号：F224307
分子式：C26H36O3
分子量：396.56
分子式：C26H36O3
分子量：396.56
产品类型
规格
价格
是否有货
1mg
询价
询价
5mg
询价
询价
10mg
询价
询价
结构图
CAS No: 180713-37-5
产品详情
生物活性：
LG100754 (UVI 2112) is a RXR dimers modulater. LG100754 acts as a RXR:RXR homodimer antagonist, but functions as a agonist towards RXR:PPARα and RXR:PPARγ heterodimers. LG100754 is an insulin sensitizer that functions through RXR.
体内研究：
LG100754 (100 mg/kg) completely blocks the increase in glucose levels, suggesting that LG100754 can improve insulin resistance in vivo.
体外研究：
LG100754 is a selective activator of endogenous RXR heterodimers.LG100754 can also improve TNFα-mediated insulin resistance in mature adipocytes.LG100754 acts as a bona fide activator of endogenous RXR:PPARγ heterodimers and regulator of insulin-dependent signaling pathways.
LG100754 (UVI 2112) is a RXR dimers modulater. LG100754 acts as a RXR:RXR homodimer antagonist, but functions as a agonist towards RXR:PPARα and RXR:PPARγ heterodimers. LG100754 is an insulin sensitizer that functions through RXR.
体内研究：
LG100754 (100 mg/kg) completely blocks the increase in glucose levels, suggesting that LG100754 can improve insulin resistance in vivo.
体外研究：
LG100754 is a selective activator of endogenous RXR heterodimers.LG100754 can also improve TNFα-mediated insulin resistance in mature adipocytes.LG100754 acts as a bona fide activator of endogenous RXR:PPARγ heterodimers and regulator of insulin-dependent signaling pathways.
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