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编 号:F218372
分子式:C21H14ClN3O
分子量:359.81
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10mM*1mL in DMSO
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1mg
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5mg
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10mg
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25mg
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生物活性:
KL044, a stabilizer of the clock protein cryptochrome (CRY) , is a potent chemical probe with a pEC50 value of 7.32, leading to the extension of the circadian period and repression of Per2 activity.

体外研究:
KL044 (0-3.7 μM; 8 h) effectively stabilizes the CRY1-LUC fusion protein without affecting the stability of LUC in the HEK293 stable cell line.
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