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编 号:F218162
分子式:C27H32F2N8
分子量:506.59
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10mM*1mL in DMSO
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1mg
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5mg
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10mg
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50mg
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生物活性:
CDK4/6-IN-2 is a potent CDK4 and CDK6 inhibitor extracted from patent US20180000819A1, Compound 1, has IC50s of 2.7 and 16 nM for CDK4 and CDK6, respectively.

体外研究:
CDK4/6-IN-2 inhibits H358, H441, PC3, MV-4-11, JeKo-1, SW780, and HGC-27 cells with IC50s of 290.9, 147.8, 260.5, 139, 36.98, 162.5, and 316.4 nM, respectively.
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