产品
编 号：F218130
分子式：C32H58N11O14P3S
分子量：945.85
分子式：C32H58N11O14P3S
分子量：945.85
产品类型
规格
价格
是否有货
1mg
询价
询价
2mg
询价
询价
结构图
CAS No: 1800401-93-7
产品详情
生物活性：
ATP-polyamine-biotin, the first cell-permeable ATP analogue, is an efficient kinase cosubstrate. ATP-polyamine-biotin promotes biotin labeling of kinase substrates in live cells.
体外研究：
ATP-polyamine-biotin (APB) is incubated with PKA kinase and full-length protein substrate, myelin basic protein (MBP). Biotinylation was observed only in presence of kinase. In addition, MBP biotinylation was lost in the absence of ATP-polyamine-biotin, in presence of the kinase inhibitor staursporine or upon incubation with acid due to cleavage of phosphoramidate bond.Biotinylated kemptide product is observed only in the presence of APB cosubstrate.
ATP-polyamine-biotin, the first cell-permeable ATP analogue, is an efficient kinase cosubstrate. ATP-polyamine-biotin promotes biotin labeling of kinase substrates in live cells.
体外研究：
ATP-polyamine-biotin (APB) is incubated with PKA kinase and full-length protein substrate, myelin basic protein (MBP). Biotinylation was observed only in presence of kinase. In addition, MBP biotinylation was lost in the absence of ATP-polyamine-biotin, in presence of the kinase inhibitor staursporine or upon incubation with acid due to cleavage of phosphoramidate bond.Biotinylated kemptide product is observed only in the presence of APB cosubstrate.
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