产品
编 号：F217925
分子式：C47H44ClFN6O6S
分子量：875.41
分子式：C47H44ClFN6O6S
分子量：875.41
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
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1mg
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5mg
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10mg
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25mg
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结构图
CAS No: 1799631-75-6
产品详情
生物活性：
MIK665 (S-64315), derived from S63845, is a myeloid cell leukemia sequence 1 (MCL1) inhibitor. MIK665 has an IC50 of 1.81 nM for MCL1.
体外研究：
MIK665 (S-64315) has similar synergistic effects as S63845, when combined with ABT-199. The combination S64315 (0.156-10 μM) and ABT-199 (625 nM) has similar efficacy in reducing the cell viability of representative melanoma lines (MB2141, MB3616, MB3961, MB4667, A375, and 1205Lu cells).?MIK665 is extracted from patent WO2016207225A1, compound Preparation 13, and inhibits H929 cell with an IC50 of 250 nM.
MIK665 (S-64315), derived from S63845, is a myeloid cell leukemia sequence 1 (MCL1) inhibitor. MIK665 has an IC50 of 1.81 nM for MCL1.
体外研究：
MIK665 (S-64315) has similar synergistic effects as S63845, when combined with ABT-199. The combination S64315 (0.156-10 μM) and ABT-199 (625 nM) has similar efficacy in reducing the cell viability of representative melanoma lines (MB2141, MB3616, MB3961, MB4667, A375, and 1205Lu cells).?MIK665 is extracted from patent WO2016207225A1, compound Preparation 13, and inhibits H929 cell with an IC50 of 250 nM.
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