产品
编 号：F215949
分子式：C56H96N10O19
分子量：1213.42
分子式：C56H96N10O19
分子量：1213.42
产品类型
规格
价格
是否有货
1mg
询价
询价
5mg
询价
询价
10mg
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询价
25mg
询价
询价
50mg
询价
询价
100mg
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询价
结构图
CAS No: 179463-17-3
产品详情
生物活性：
Caspofungin (MK-0991) diacetate is a potent antifungal agent. Caspofungin diacetate inhibits the synthesis of the fungal cell wall component β-(l,3)-D-glucan.
体内研究：
Caspofungin diacetate (1-8 mg/kg；腹腔注射；每日一次，持续 7 天) 能够穿透小鼠的 CNS 并达到可减少大脑念珠菌负荷的浓度。 Caspofungin diacetate (0.41-41 μM；腹腔注射；持续 5 周；雄性 C57BL/6 小鼠) 在小鼠玻璃体浓度为 0.41 至 4.1 μM 时是一种安全的抗真菌剂。Animal Model:Complement component 5-deficient DBA/2N mice
Dosage:1, 2, 4 and 8 mg/kg
Administration:Intraperitoneal injection; daily, for 7 days
Result:Reduced the concentration of Candida load in the brain.
Animal Model:Male C57BL/6 mice
Dosage:0.41, 1.2, 2.5, 4.1, and 41 μM
Administration:Intraperitoneal injection; for 5 weeks
Result:Had nonsignificant alterations in their ERG waveforms from 0.41 to 4.1 μM.
Caspofungin (MK-0991) diacetate is a potent antifungal agent. Caspofungin diacetate inhibits the synthesis of the fungal cell wall component β-(l,3)-D-glucan.
体内研究：
Caspofungin diacetate (1-8 mg/kg；腹腔注射；每日一次，持续 7 天) 能够穿透小鼠的 CNS 并达到可减少大脑念珠菌负荷的浓度。 Caspofungin diacetate (0.41-41 μM；腹腔注射；持续 5 周；雄性 C57BL/6 小鼠) 在小鼠玻璃体浓度为 0.41 至 4.1 μM 时是一种安全的抗真菌剂。Animal Model:Complement component 5-deficient DBA/2N mice
Dosage:1, 2, 4 and 8 mg/kg
Administration:Intraperitoneal injection; daily, for 7 days
Result:Reduced the concentration of Candida load in the brain.
Animal Model:Male C57BL/6 mice
Dosage:0.41, 1.2, 2.5, 4.1, and 41 μM
Administration:Intraperitoneal injection; for 5 weeks
Result:Had nonsignificant alterations in their ERG waveforms from 0.41 to 4.1 μM.
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