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编 号:F215818
分子式:C24H26BrFN4O5S
分子量:581.45
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生物活性:
HEC72702 is a potent and orally active hepatitis B virus capsid inhibitor with an EC50 values of 0.039 μM. HEC72702 dose-dependently reduced HBV DNA in both the plasma and livers.

体内研究:
HEC72702 (50、100 mg/kg;口服;每日一次,连续 7 天) 剂量依赖性地减少血浆和肝脏中的 HBV DNA 拷贝数。Animal Model:6-7 weeks, 16-18 g, Female BALB/c mice(HDI mouse model)
Dosage:50, 100 mg/kg
Administration:P.o.; daily for 7 days
Result:Demonstrated a dose-dependent reduction of HBV DNA in the plasma of infected mice.
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