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编 号:F215600
分子式:C17H14N2O3
分子量:294.3
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10mM*1mL in DMSO
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2mg
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5mg
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10mg
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25mg
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50mg
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100mg
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生物活性:
PHCCC is a Group I mGluR antagonist with an IC50 of 3 μM. PHCCC is a selective positive modulator of mGlu4 receptor. Antiparkinsonian effect.

体内研究:
PHCCC (75 nmol/2.5 μl; intracerebroventricular) produces an antiparkinsonian effect in a dopamine depletion akinesia model.

体外研究:
PHCCC potentiated the effect of L-(+)-2-amino-4-phosphonobutyric acid (L-AP4) in inhibiting transmission at the striatopallidal synapse.
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